Dr Medica Dermatologic Anti-Acne Face Cream Day & Night. It clears existing acne and prevents new spots from forming. Balances the functioning of sebaceous glands, visibly tightens pores, and brightens and soothes the skin. The specially developed TR-T 70mg/1g formula carries several strong active ingredients that have a direct effect on acne-prone skin. These ingredients include an Azelaic Acid Derivative, an anti-bacterial agent that reduces oiliness and uneven pigmentation. Mandelic Acid, which also has anti-bacterial effects as well as soothing spots and balancing the skin tone. Lactobionic Acid gently exfoliates, smooths and moisturizes the skin while Niacinamide strengthens and protects it. Responsible packaging. Cruelty-free & vegan-friendly. Directions of use: Use twice daily, in the morning and evening. Massage cream into cleansed skin on the face, and leave to absorb. The cream is an ideal base for applying makeup. When applying the cream during the day, use UV protection products.